产品编号：H245648
产品规格：5g
产品价格：面议
| 标准品编号: | H245648 |
| 名称: | Hemin Chloride (Technical grade) |
| 别名: | 1,3,5,8-Tetramethyl-2,4-divinylporphine-6,7-dipropionic Acid ferrichloride Chloro[dihydrogen 3,7,12,17-Tetramethyl-8,13-divinyl-2,18-porphinedipropionato(2-)]iron; Chlorohemin; Chloroprotoferriheme; Chloroprotohemin; Ferric Hemin; Ferriheme; Ferriheme Chloride; Ferriporphyrin Chloride; Ferriprotoporphyrin; Ferriprotoporphyrin IX; Ferriprotoporphyrin IX Chloride; Hemin; Hemin IX; Hemin Chloride; Iron(III) Protoporphyrin Chloride; KJB 003; Panhematin; Protoferriheme; Protohemin; Protohemin Chloride; Teichmann's Crystals |
| CAS号: | 16009-13-5 |
| 参考CAS号: | free acid 752166-39-5 |
| 分子式: | C₃₄H₃₂ClFeN₄O₄ |
| 外观: | Dark Purple to Black Solid |
| 熔点: | >300°C |
| 分子量: | 651.94 |
| 储存: | Amber Vial, -20°C Freezer |
| 溶解度: | Aqueous Base (Slightly), Pyridine (Slightly) |
| 种类: | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | Hemin chloride is a porphyrin complex heme oxygenase-1 inducer with acts in cellular protection and control. At a concentration of 20 mM Hemin chloride demonstrated the significance of heme in myotube maturation by increasing size, number, cross-striations, and contraction frequency and strength of myotubes. The compound has been observed to induce cGMP formation through induction of guanylate cyclase. Hemin chloride has been noted to stimulate calcium-dependent K+ channels and modulate fluid transport and Na+ in the loop of henle in rat studies. Hemin has also been documented to give rise to active chloride secretion in Caco-2 cells. In cadmium injured rat testes, hemin chloride demonstrated anti-apoptotic, antiinflamatory and antioxidant properties. Through reactive oxygen species of ERK |
| 参考文献 | |
