产品编号：G797700

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	G797700
名称:	GSK 4112
别名:	N-[(4-Chlorophenyl)methyl]-N-[(5-nitro-2-thienyl)methyl]glycine 1,1-Dimethylethyl Ester;
CAS号:	1216744-19-2
分子式:	C₁₈H₂₁ClN₂O₄S
分子量:	396.89
种类:	Building Blocks;
应用:	GSK 4112 is a synthetic ligand for REV-ERBα, a member of the nuclear receptor superfamily that functions as a receptor for the porphoryin heme. GSK 4112 mimics the action of heme acting as agonist and suppresses the expression of REV-ERBα target genes involved in gluconeogenesis.
参考文献	Kojetin, D. et al.: ACS Chem. Biol., 6, 131 (2011); Grant, D. et al.: ACS Chem. Biol., 5, 925 (2010);