产品编号：G797450

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	G797450
名称:	GSK 1059615 Sodium Salt Hydrate
别名:	(5Z)-5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidinedione Sodium Salt Hydrate;
CAS号:	1356195-42-0
参考CAS号:	Free acid/Anhydrous: 958852-01-2
分子式:	C₁₈H₁₁N₃NaO₂S•xH₂O
外观:	淡黄色固体
熔点:	>290°C (dec.)
分子量:	355.35
储存:	冰箱
溶解度:	DMSO, Methanol
种类:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	GSK 1059615 is a potent inhibitor of PI 3-kinase α (PI3Kα). GSK 1059615 inhibits proliferation in BT474 cells and attenuates MAPK signaling.
参考文献	Saadia, et al.: Clin. Cancer Res., 15, 3029 (2009), Knight, et al.: ACS Med. Chem. Lett., 1, 39 (2010),