产品编号：G797415
产品规格：100mg
产品价格：面议
| 标准品编号: | G797415 |
| 名称: | GSK 5072 Dihydrochloride |
| 别名: | 5-(((4-Chlorobenzyl)(pyridin-3-ylmethyl)amino)methyl)thiophene-2-carbonitrile Dihydrochloride; 5-[[[(4-Chlorophenyl)methyl](3-pyridinylmethyl)amino]methyl]-2-thiophenecarbonitrile Dihydrochloride; |
| 参考CAS号: | Free Base: 1438071-23-8 |
| 分子式: | C₁₉H₁₆ClN₃S • 2(HCl) |
| 外观: | 白色至淡黄色固体 |
| 熔点: | >137ºC (dec.) |
| 分子量: | 353.8723646 |
| 储存: | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| 溶解度: | DMSO (Slightly, Heated), Methanol (Very Slightly, Heated) |
| 种类: | Research Tools; Molecular Biology; |
| 应用: | GSK 5072 Dihydrochloride is an analogue of GSK 4112 (G797700) which is a synthetic ligand for REV-ERBα, a member of the nuclear receptor superfamily that functions as a receptor for the porphoryin heme. GSK 4112 mimics the action of heme acting as agonist and suppresses the expression of REV-ERBα target genes involved in gluconeogenesis. |
| 参考文献 | |
