产品编号：G766313

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	G766313
名称:	GNF-6231
别名:	N-[5-(4-Acetyl-1-piperazinyl)-2-pyridinyl]-2'-fluoro-3-methyl[2,4'-bipyridine]-5-acetamide
CAS号:	1243245-18-2
分子式:	C₂₄H₂₅FN₆O₂
分子量:	448.49
种类:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	GNF-6231 was used in the study to prepare N-​(hetero)​aryl, 2-​(hetero)​aryl-​substituted acetamides for use as Wnt signaling modulators. Blockade of aberrant Wnt signaling is an attractive therapeutic approach in multiple cancers.
参考文献	Cheng, D., et al.: PCT Int. Appl. (2010), WO 2010101849 A1 20100910; Cheng, D., et al.: ACS Med. Chem. Lett., 7, 676 (2016); Che, J., et al.: PCT Int. Appl. (2014), WO 2014141038 A2 20140918