产品编号：G797600
产品规格：5mg
产品价格：面议
| 标准品编号: | G797600 |
| 名称: | GSK360A |
| 别名: | N-[[1-(2-Cyclopropylethyl)-6-fluoro-1,2-dihydro-4-hydroxy-2-oxo-3-quinolinyl]carbonyl]glycine; N-[[1-(2-Cyclopropylethyl)-6-fluoro-4-hydroxy-2-oxo-1,2-dihydro-3-quinolinyl]carbonyl]glycine; |
| CAS号: | 931399-19-8 |
| 参考CAS号: | 680590 |
| 分子式: | C₁₇H₁₇FN₂O₅ |
| 外观: | Beige Solid |
| 熔点: | 194-198°C (dec.) |
| 分子量: | 348.33 |
| 储存: | 冰箱 |
| 溶解度: | DMSO, Methanol |
| 种类: | Research Tools; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | GSK360A orally active HIF-PHD inhibitor. GSK360A exerts systemic and local effects by stabilizing HIF-1α signaling and improves long-term ventricular function, remodeling, and vascularity in a model of established ventricular dysfunction. These findings suggest that GSK360A may be suitable for the treatment of post-MI remodeling and heart failure. |
| 参考文献 | |
