产品编号：F336500

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	F336500
名称:	FIIN-1
别名:	N-[3-[[3-(2,6-Dichloro-3,5-dimethoxyphenyl)-7-[[4-(diethylamino)butyl]amino]-3,4-dihydro-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl]phenyl]-2-propenamide; FGFR Irreversible Inhibitor 1; Fibroblast Growth Factor Receptor Irreversible Inhibitor 1; N-[3-[[3-(2,6-Dichloro-3,5-dimethoxyphenyl)-7-[[4-(diethylamino)butyl]amino]-3,4-dihydro-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl]phenyl]acrylamide;
CAS号:	1256152-35-8
分子式:	C₃₂H₃₉Cl₂N₇O₄
分子量:	656.6
种类:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	FIIN-1 is a fibroblast growth factor receptor (FGFR) Irreversible Inhibitor 1 (1).The fibroblast growth factor receptor tyrosine kinases are promising therapeutic targets in a number of cancers and FIIN-1 is a useful probe of FGFR-dependent cellular phenomena and may assist in the development of therapeutically relevant irreversible inhibitors, particularly for wild-type and drug-resistant forms of FGFR kinases.
参考文献	(1) Zhou, W. et al.: Chem. Biol., 17, 285 (2010)