产品编号：F621730

产品规格：1mg

产品价格：面议

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产品详情

标准品编号:	F621730
名称:	(3R,5R,6E)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid 1,1-Dimethylethyl Ester
别名:	[R-[R*,R*-(E)]]-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid 1,1-Dimethylethyl Ester; (3R,5R,E)-t-Butyl 7-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)-3,5-dihydroxyhept-6-enoate
CAS号:	194934-98-0
分子式:	C₂₈H₃₄FNO₄
外观:	Light Yellow Crystalline Solid
分子量:	467.57
溶解度:	Chloroform, Dichloromethane, Methanol
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(3R,5R,6E)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid 1,1-Dimethylethyl Ester is an intermediate in synthesizing rel-(3R,5R)-Fluvastatin Sodium (F601215), which is a derivative of Fluvastatin (F601250), a synthetic HMG-CoA reductase inhibitor. Antilipemic.
参考文献	Yuan, J., et al.: Atherosclerosis, 87, 147 (1991); Tse, F.L.S., et al.: J. Clin. Pharmacol., 32, 630 (1992); Dain, J.G., et al.: Drug Metab. Disposit., 21, 567 (1993)