产品编号：F595780

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	F595780
名称:	(R,E)-7-(4-(4-Fluorophenyl)-2-(2-hydroxy-N,2-dimethylpropylsulfonamido)-6-isopropylpyrimidin-5-yl)-3-hydroxy-5-oxohept-6-enoate(Rosuvastatin Impurity)
别名:	(6E)-7-(4-(4-Fluorophenyl)-2-[[(2-hydroxy-2-methylpropyl)sulfonyl)](methyl)amino]-6-isopropylpyrimidine-5-yl}(3R, 5S)-3,5-dihydroxyhept-6-enoic acid] Calcium Salt
分子式:	C₂₅H₃₁FN₃O₇S•1/2Ca
分子量:	556.63
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(R,E)-7-(4-(4-Fluorophenyl)-2-(2-hydroxy-N,2-dimethylpropylsulfonamido)-6-isopropylpyrimidin-5-yl)-3-hydroxy-5-oxohept-6-enoate, is an impurity of Rosuvastatin (R700500), which is a selective, competitive HMG-CoA reductase inhibitor. It is used primarily for the treatment of dyslipidemia.
参考文献	Watanabe, M., et al.: Bioorg. Med. Chem., 5, 437 (1997), Lee, E., et al.: Clin. Pharmacol. Ther., 78, 330 (2005), Ferdinand, K.C., et al.: Am. J. Cardiol., 97, 229 (2006),