产品编号：F592005

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	F592005
名称:	(2S-cis)-5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione
别名:	5-Fluoro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione; 5-Fluoro-3'-thia-2',3'-dideoxyuridine
CAS号:	145281-92-1
分子式:	C₈H₉FN₂O₄S
分子量:	248.23
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites; Carbohydrates and Oligosaccharides;
应用:	5-Fluoro-3'-thia-2',3'-dideoxyuridine is an impurity ofent-Emtricitabine (E525005), areverse transcriptase inhibitor and an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. In addition,ent-Emtricitabine (E525005) is anucleoside analog structurally related to Lamivudine (L172500).
参考文献	Mellors, J., et al.: Science, 72, 1167 (1996), Reimann, K., et al.: J. Virol., 79, 8878 (2005), Rose, J., et al.: J. Biol. Chem., 280, 7413 (2005), Acierno, P., et al.: J. Immunol., 176, 5338 (2006)