产品编号：E916615

产品规格：500mg

产品价格：面议

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产品详情

标准品编号:	E916615
名称:	Ethyl 3-[2-(3,4-Dimethoxyphenyl)-N-methylacetamido]propanoate
分子式:	C₁₆H₂₃NO₅
外观:	Brown Oil
分子量:	309.36
溶解度:	DCM, Ether, Ethyl Acetate, Methanol
种类:	Standards; Miscellaneous;
应用:	Ethyl 3-[2-(3,4-Dimethoxyphenyl)-N-methylacetamido]propanoate is an intermediate in the synthesis of Tolafentrine (T531000), which is a dual-selective phosphodiesterase 3/4 inhibitor used in chronic experimental pulmonary hypertension.
参考文献	Huxtable, R., et al.: Pharmacol. Ther., 47, 371 (1990), Tanaka, K., et al.: Cancer Res., 55, 2927 (1995), Wagner, R., et al.: J. Pharmacol. Exp. Ther., 282, 1650 (1997), Cowan, K., et al.: Nat. Med., 6, 698 (2000), Shankavaram, U., et al.: J. Biol. Chem., 276, 19027 (2001),