产品编号：E926495

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	E926495
名称:	N-[4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-N'-[4-[[6-(methylamino)-4-pyrimidinyl]oxy]phenyl]urea
别名:	AST 487; NVP-AST 487;
CAS号:	630124-46-8
分子式:	C₂₆H₃₀F₃N₇O₂
外观:	白色至淡黄色固体
熔点:	162-164°C
分子量:	529.56
储存:	冰箱保存
溶解度:	DMSO (Slightly), Methanol (Slightly)
种类:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	N-[4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-N'-[4-[[6-(methylamino)-4-pyrimidinyl]oxy]phenyl]urea is an inhibitor of RET, FLT3, KDR, c-Abl and c-Kit. Also, it prevent the growth of human thyroid cancer cells.
参考文献	Weisberg, E., et al.: Genes Cancer, 1, 1021-1032 (2010);