产品编号：E924295
产品规格：100mg
产品价格：面议
| 标准品编号: | E924295 |
| 名称: | 4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)-benzenamine |
| 别名: | 3-Trifluoromethyl-4-(4-ethylpiperazin-1-ylmethyl)phenylamine; 4-((4-Ethylpiperazine-1-yl)methyl)-3-(trifluoromethyl)aniline; 4-(4-Ethylpiperazin-1-ylmethyl)-3-trifluoromethylaniline; [4-(4-Ethylpiperazin-1-ylmethyl)-3-trifluoromethylphenyl]amine; |
| CAS号: | 630125-91-6 |
| 分子式: | C₁₄H₂₀F₃N₃ |
| 外观: | Yellow Solid |
| 分子量: | 287.32 |
| 溶解度: | Dichloromethane; |
| 种类: | Building Blocks; Miscellaneous; |
| 应用: | 4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)-benzenamine is one of the key reactants with N-[1-(4-Aminophenyl)-1H-pyrrolo[3,2-c]pyridin-4-yl]benzamide used in the synthesis of a pyrrolo[3,2-c]pyridine derivative [N-[1-[4-[[[[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenyl]-1H-pyrrolo[3,2-c]pyridin-4-yl]benzamide (I)], an anticancer diarylurea derivative with multiple-kinase inhibitory effect; Also, it is an intermediate used in the synthesis of N-[4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-N'-[4-[[6-(methylamino)-4-pyrimidinyl]oxy]phenyl]urea (E926495), which is an inhibitor of RET, FLT3, KDR, c-Abl and c-Kit. Also, it prevent the growth of human thyroid cancer cells. |
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