产品编号：E921670

产品规格：10g

产品价格：面议

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产品详情

标准品编号:	E921670
名称:	Ethyl 3,4-O-isopropylideneshikimate
别名:	[3aR-(3aα,7α,7aα)]-3a,6,7,7a-Tetrahydro-7-hydroxy-2,2-dimethyl-1,3-benzodioxole-5-carboxylic Acid Ethyl Ester; (3aR,7R,7aS)-Ethyl 7-Hydroxy-2,2-dimethyl-3a,6,7,7a-tetrahydrobenzo[d][1,3]dioxole-5-carboxylate
CAS号:	136994-78-0
分子式:	C₁₂H₁₈O₅
外观:	白色至Pale Yellow Waxy Solid
熔点:	55-58°C
分子量:	242.27
储存:	冰箱保存
溶解度:	Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
种类:	Building Blocks; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Ethyl 3,4-O-isopropylideneshikimate is an acetonide used in the synthesis of Oseltamivir phosphate (O701000), an orally active inhibitor of influenza virus neuraminidase; converted in vivo to the active acid metabolite. An antiviral drug.
参考文献	Nie, L., Shi, X.: Tetrahedron: Asymm., 20, 124 (2009); Oliyai, R., et al.: Pharm. Res., 15, 1300 (1998); Kim, C.U., et al.: Med. Chem. Res., 8, 392 (1998); Hayden, F.G., et al.: N. Engl. J. Med., 341, 1336 (1999); Treanor, J.J., et al.: J. Am. Med. Assoc., 283, 1016 (2000)

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