产品编号：E919010

产品规格：250mg

产品价格：面议

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产品详情

标准品编号:	E919010
名称:	Ethyl 2-​(4-​Bromophenyl)​-​2-​methylpropanoate
别名:	2-(4-Bromophenyl)-2-methylpropionic Acid Ethyl Ester;Ethyl 2-(4-bromophenyl)-2-methylpropanoate; Ethyl α,α-Dimethyl-p-bromophenylacetate;
CAS号:	32454-36-7
分子式:	C₁₂H₁₅BrO₂
分子量:	271.15
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Ethyl 2-​(4-​Bromophenyl)​-​2-​methylpropanoate is an intermediate of Alectinib (C183360), a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth.
参考文献	Kinoshita, K. et al.: J. Med. Chem., 64, 6286 (2011); Sakamoto, H., et al.: Cancer Cell., 19, 679 (2011); Kinoshita, K., et al.: Bio-org. Medn., 20, 1271 (2012);