产品编号：E907782

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	E907782
名称:	Ethyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate-d9
别名:	2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic-d9 Acid Ethyl Ester; Ethyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate-d9; Febuxostat-d9 Ethyl Ester
参考CAS:	未标记：160844-75-7
分子式:	C₁₈H₁₁D₉N₂O₃S
外观:	白色固体
分子量:	353.48
溶解度:	Dichloromethane
种类:	Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Ethyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate-d9 is an intermediate in the synthesis of Febuxostat-d9 (F229002). Febuxostat-d9 is the labelled analogue of Febuxostat (F229000). Febuxostat is an Xanthine oxidase/xanthine dehydrogenase inhibitor, used for treatment of hyperuricemia and chronic gout.
参考文献	Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993); Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005); Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005)