产品编号：E900105

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	E900105
名称:	(S,E)-Ethyl 5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoate
分子式:	C₂₅H₃₁NO₄
外观:	白色固体
分子量:	409.52
溶解度:	Dichloromethane, Ethyl Acetate
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites; Phenethylamines/Amphetamines;
应用:	(S,E)-Ethyl 5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoate is an intermediate in the synthesis of (2S,4R)-Sacubitril (S080905). (2S,4R)-Sacubitril is the enantiomer and an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan.
参考文献	McMurray, J., et al.: N. Eng. J. Med., 371 (2014)