产品编号：E705520

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	E705520
名称:	Ethyl 2-Amino-4-(2-hydroxyethoxy)-5-(2-methoxyethoxy)benzoateDiscontinued, see E678245
分子式:	C₁₄H₂₁NO₆
分子量:	299.32
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Ethyl 2-Amino-4-(2-hydroxyethoxy)-5-(2-methoxyethoxy)benzoate is a derivative of 2-Amino-4,5-bis(2-methoxyethoxy)benzoic Acid Ethyl Ester (A602006). 2-Amino-4,5-bis(2-methoxyethoxy)benzoic Acid Ethyl Ester is an intermediate in the synthesis of Erlotinib (E625000, HCl); a selective epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor and antineoplastic agent.
参考文献	Moyer, J.D., et al.: Cancer Res., 57, 4838 (1997); Hidalgo, M., et al.: J. Clin. Oncol., 19, 3267 (2001); Perez-Soler, R., et al.: J. Clin. Oncol., 22, 3238 (2004); Blackhall, F.H., et al.: Expert Opin. Pharmacother., 6, 995 (2005)