产品编号：E594500

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	E594500
名称:	ERB 041
别名:	7-Ethenyl-2-(3-fluoro-4-hydroxyphenyl)-5-benzoxazolol; 2-(3-Fluoro-4-hydroxyphenyl)-7-vinyl-1,3-benzoxazol-5-ol; 2-(3-Fluoro-4-hydroxyphenyl)-7-vinylbenzoxazol-5-ol; Prinaberel;
CAS号:	524684-52-4
分子式:	C₁₅H₁₀FNO₃
外观:	白色至淡黄色固体
熔点:	149152°C (dec.)
分子量:	271.24
储存:	冰箱保存
溶解度:	DMSO (Slightly), Methanol (Slightly)
种类:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	ERB 041 is a potent ERβ agonist; displays >200-fold selectivity for ERβ over ERα (IC50 values are 5 and 1216 nM for human ERβ and ERα; 3.1 and 620 nM for rat ERβ and ERα; and 3.7 and 750 nM for mouse ERβ and ERα respectively).
参考文献	Harris, et al.: Endocrinology, 144. 4241 (2003); Malamas, et al.: J. Med. Chem., 47, 5021 (2004); Cvoro, et al.: J. Immunol., 180, 630 (2008),

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