产品编号：E588665

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	E588665
名称:	Epirubicin Glucuronide Sodium Salt (α/β mixture)
别名:	(8S,10S)-10-[(3-Amino-2,3,6-trideoxy-4-O-D-glucopyranuronosyl-α-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione Sodium Salt; (8S-cis)-10-[(3-Amino-2,3,6-trideoxy-4-O-D-glucopyranuronosyl-α-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy- 5,12-naphthacenedione Sodium Salt; 4'-O-D-Glucuronyl-4'-epirubicin Sodium Salt
参考CAS:	Free Acid: 92137-84-3
分子式:	C₃₃H₃₆NNaO₁₇
分子量:	741.63
种类:	Standards; Enzyme Activators and Inhibitors; Carbohydrates and Oligosaccharides;
应用:	Epirubicin glucuronide is a prodrug and a metabolite of Epirubicin (HCl: E588650). Epirubicin is an antineoplastic agent that is used as primary treatment for advanced breast cancer. Epirubicin is also used in conjunction with other cytotoxic agents to treat a number of cancerous malignancies such as ovarian cancer.
参考文献	Cersosimo, R. & Hong, W.: J. Clin. Oncol., 4, 425 (1986); Focan, C., et al.: J. Clin. Oncol., 11, 1253 (1993); Houba, P., et al.: Biochem. Pharm., 52, 455 (1996); Innocenti, F., et al.: Drug Metab. Disp., 29, 686 (2001); Plosker, G. & Faulds, D.: Drugs, 45, 788 (1993)