产品编号：E588050

产品规格：25mg

产品价格：面议

---

产品详情

标准品编号:	E588050
名称:	9β,11β-Epoxy Eplerenone
别名:	(2'R,4aS,4bS,6aS,9aS,9bR,10R)-Methyl 4a,6a-dimethyl-2,5'-dioxo-3,4,4a,4',5a,5',6,6a,8,9,9a,9b,10,11-tetradecahydro-2H,3'H-spiro[cyclopenta[1,2]phenanthro[4,4a-b]oxirene-7,2'-furan]-10-carboxylate
分子式:	C₂₄H₃₀O₆
分子量:	414.49
种类:	Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; Steroids;
应用:	9β,11β-Epoxy Eplerenone is an impurity of Eplerenone (E588775), a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.
参考文献	de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), Delyani, J.A., et al.: Cardiovasc. Drug Rev., 19, 185 (2001), Burgess, E., et al.: Expert. Opin. Pharmacother., 5, 2573 (2004), Ravis, W.R., et al.: J. Clin. Pharmacol., 45, 810 (2005),