产品编号：E578300

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	E578300
名称:	Epiberberine Chloride
别名:	7,8,13,13a-Tetradehydro-2,3-dimethoxy-9,10-(methylenedioxy)berbinium Chloride;
CAS号:	889665-86-5
参考CAS:	Free Base: 6873-09-2
分子式:	C₂₀H₁₈NO₄ ⁺ •Cl⁻
外观:	Orange to Dark Orange Solid
熔点:	>253°C (dec.)
分子量:	336.363545
储存:	Amber Vial, -20°C Freezer, Under inert atmosphere
溶解度:	DMSO (Slightly), Methanol (Slightly)
种类:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Epiberberine Chloride, is a natural bioactive alkaloid, an isomer of Berberine (B318150), an isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells.
参考文献	Zhang, X. et al.: Cancer Res., 70, 9895 (2010); Lin, H.L. et al.: Cancer 85, 1937(1999); Schumacher, M.A. et al.: Science, 294, 2158 (2001); Fukuda, K. et al.: J. Ethno., 66, 227(1999); Liu, X. et al.: J. Pharm. Biomed. Anal., 98, 463 (2014);