产品编号：D528822
产品规格：2.5mg
产品价格：面议
| 标准品编号: | D528822 |
| 名称: | Dolutegravir-d3 RR Isomer |
| 别名: | (4R,12aR)-N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pPyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide-d3 |
| 参考CAS: | 未标记：1357289-29-2 |
| 分子式: | C₂₀H₁₆D₃F₂N₃O₅ |
| 分子量: | 422.4 |
| 种类: | Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Anti-virals/Anti-retrovirals; |
| 应用: | Isotope labelled Dolutegravir RR Isomer is an isomer of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector. |
| 参考文献 | |
