产品编号：D528815
产品规格：10mg
产品价格：面议
| 标准品编号: | D528815 |
| 名称: | Dolutegravir O-β-D-Glucoside |
| 别名: | N-[(2,4-difluorophenyl)methyl]-7-(β-D-glucopyranosyloxy)-3,4,6,8,12,12a-hexahydro-4-methyl-6,8-dioxo2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, -, (4R,12aS)- |
| CAS号: | 1822365-49-0 |
| 分子式: | C₂₆H₂₉F₂N₃O₁₀ |
| 分子量: | 581.52 |
| 种类: | Standards; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | Dolutegravir O-β-D-Glucoside is a metabolite of Dolutegravir (D528800); a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector. |
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