产品编号：D487250

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	D487250
名称:	2-(2,2-Diphenyl-1,3-benzodioxol-5-yl)-5,7-dihydroxy-3-(phenylmethoxy)-4H-1-benzopyran-4-one
CAS号:	498548-17-7
分子式:	C₃₅H₂₄O₇
外观:	Yellow Solid
分子量:	556.56
溶解性:	Dichloromethane, Methanol
种类:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	2-(2,2-Diphenyl-1,3-benzodioxol-5-yl)-5,7-dihydroxy-3-(phenylmethoxy)-4H-1-benzopyran-4-one is an intermediate in the synthesis of Quercetin Dihydrate (Q509500), which is a lavonoid with anticancer activity. It is a mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Quercetin has antiproliferative effects on cancer cell lines, reduces cancer cell growth via type II estrogen receptors, and arrests human leukemic T cells in late G1 phase of the cell cycle.
参考文献	Graziani, Y. et al.: J. Biochem., 135, 583 (1983); Levy, J. et al.: Biochem. Biophys. Res. Comm., 123, 1227 (1984); Wei, Y.Q. et al.: Cancer Res., 54, 4952 (1994);