产品编号：D486993

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	D486993
名称:	N-[2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethyl]-carbamic Acid 1,1-Dimethylethyl Ester
别名:	tert-Butyl (2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethyl)carbamate
CAS号:	1957235-57-2
分子式:	C₂₀H₂₄N₄O₆
外观:	Yellow Solid
分子量:	416.43
溶解性:	Dichloromethane, Ethyl Acetate, Methanol
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	N-[2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethyl]-carbamic Acid 1,1-Dimethylethyl Ester is an intermediate in the synthesis of N-[2-Aminoethyl] Pomalidomide TFA Salt (A6095150. N-[2-Aminoethyl] Pomalidomide TFA is a thalidomide derivative, a potent inhibitor of TNF-α production. It is an anti-inflammatory and anti-tumor agent used in the treatment of multiple myeloma.
参考文献	Ruchelman, A. et al.: Bioorg. Med. Chem. Lett., 23, 360 (2013); Latif, T. et al.: Exp. Hematol. Oncol., 1, 27 (2012); Man, H. et al.: Bioorg. Med. Chem. Lett., 13, 3415 (2003); Muller, G. et al.: Bioorg. Med. Chem. Lett., 9, 1625 (1999)