产品编号：D480849

产品规格：10mg

产品价格：面议

---

产品详情

标准品编号:	D480849
名称:	2-(3,4-Dimethylphenyl)-2,4-dihydro-5-methyl-3H-pyrazol-3-one-13C4
别名:	3-Methyl-1-(3,4-xylyl)-2-pyrazolin-5-one; 3-Methyl-1-(3,4-dimethylphenyl)-2-pyrazolin-5-one
参考CAS号:	未标记：18048-64-1
分子式:	C₈¹³C₄H₁₄N₂O
外观:	Yellow Solid
分子量:	206.22
溶解性:	DMSO
种类:	Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	2-(3,4-Dimethylphenyl)-2,4-dihydro-5-methyl-3H-pyrazol-3-one-13C4 is an intermediate in the synthesis of Eltrombopag-13C4 (E508002), which is an agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia.
参考文献	Bussel, J., et al.: New Eng. J. Med., 357, 2237 (2007); Marsilje, T., et al.: Bioorg. Med. Chem. Lett., 18, 5259 (2008); Alper, P., et al.: Bioorg. Med. Chem. Lett., 18, 5255 (2008)