产品编号：D480268
产品规格：50mg
产品价格：面议
| 标准品编号: | D480268 |
| 名称: | (6R,7R)--[(1Z)-2-(2,4-Dinitrophenyl)ethenyl]-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid (4-Methoxyphenyl)methyl Ester |
| 别名: | (6R,7R)-4-Methoxybenzyl 3-((E)-2,4-Dinitrostyryl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate |
| CAS号: | 828919-20-6 |
| 分子式: | C₂₉H₂₄N₄O₉S₂ |
| 外观: | Dark Red Solid |
| 分子量: | 636.65 |
| 溶解性: | Dichloromethane |
| 种类: | Standards; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | (6R,7R)--[(1Z)-2-(2,4-Dinitrophenyl)ethenyl]-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid (4-Methoxyphenyl)methyl Ester is an intermediate in synthesizing Nitrocefin (N493815), a chromogenic β-lactamase substrate that undergoes colour change from yellow to red as the amide bond in the β-Lactam ring is hydrolyzed by β-lactamase. Nitrocefin undergoes colour changes induced by lactamases produced by Gram-positive and Gram-negative bacteria. Several studies have utilized the colour changing properties of Nitrocefin for the detection of β-lactamase activity from bacterial cell extracts by isoelectric focusing and spectroscopy. Nitrocefin has also been used in studies involving β-lactamase resistant antibiotics. |
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