产品编号：D480225

产品规格：25mg

产品价格：面议

---

产品详情

标准品编号:	D480225
名称:	4-[2-[(2,4-Dimethylphenyl)thio]phenyl]-2-morpholinone
别名:	4-(2-((2,4-Dimethylphenyl)thio)phenyl)morpholin-2-one;
CAS号:	1818381-15-5
分子式:	C₁₈H₁₉NO₂S
外观:	淡黄色固体
分子量:	313.41
溶解性:	Ethyl Acetate
种类:	Standards; Miscellaneous;
应用:	4-[2-[(2,4-Dimethylphenyl)thio]phenyl]-2-morpholinone is an intermediate in synthesizing N-Hydroxy Vortioxetine O-β-D-Glucuronide Sodium Salt (H996005), which is a metabolite of Vortioxetine (V766000, HBr); a multimodal serotonergic agent which inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT.
参考文献	Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011); Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012); Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013); Uldam, H.K., et al.: Drug Metab. Dispos., 39, 2264 (2011);