产品编号：D479868

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	D479868
名称:	(3S,10R,13S)-10,13-dimethyl-17-(trifluoromethylsulfonyloxy)-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1Hcyclopenta[a]phenanthren-3-yl 2,2,2-trifluoroacetate
别名:	Abiraterone Impurity 8
杂质:	Abiraterone Impurity 8
CAS号:	1802323-89-2
分子式:	C₂₂H₂₆F₆O₅S
分子量:	516.49
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites; Steroids;
应用:	(3S,10R,13S)-10,13-dimethyl-17-(trifluoromethylsulfonyloxy)-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1Hcyclopenta[a]phenanthren-3-yl 2,2,2-trifluoroacetate is an impurity of Abiraterone (A108490), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer. (Abiraterone Impurity 8).
参考文献	Denis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389(2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005)