产品编号：D474975

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	D474975
名称:	Dimethyl 2-Methyl-4-phenyl-6-(4-((triphenylphosphoranylidene)amino)butyl)-1,4-dihydropyridine-3,5-dicarboxylate
分子式:	C₃₈H₃₉N₂O₄P
分子量:	618.7
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Dimethyl 2-Methyl-4-phenyl-6-(4-((triphenylphosphoranylidene)amino)butyl)-1,4-dihydropyridine-3,5-dicarboxylate is an intermediate used in the synthesis of Amlodipine Dimethyl Ester (A633560), a Amlodipine Besilate (A633560) impurity, which is a dihydropyridine calcium channel blocker. Used as an antianginal and antihypertensive.
参考文献	Coburn, R., et al.: J. Med. Chem., 31, 2103 (1988), Gupta, S., et al.: Eur. J. Med. Chem., 38, 867 (2003), Vazzana, I., et al.: J. Med. Chem., 50, 334 (2007); Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986); Burges, R.A., et al.: J. Cardiovasc Pharmacol., 9, 110 (1987); Packer, M., et al.: N. Engl. J. Med., 335, 1107 (1996);