产品编号：D473865

产品规格：5mg

产品价格：面议

---

产品详情

标准品编号:	D473865
名称:	(3R,4R)-4-[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]phenyl]-1-(4-fluorophenyl)-3-[2-[2-(4-fluorophenyl)-5,5-dimethyl-1,3-dioxan-2-yl]ethyl]-2-azetidinone
CAS号:	1478663-98-7
分子式:	C₃₅H₄₃F₂NO₄Si
外观:	Orange Solid
分子量:	607.8
溶解性:	DCM, Ethyl Acetate
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(3R,4R)-4-[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]phenyl]-1-(4-fluorophenyl)-3-[2-[2-(4-fluorophenyl)-5,5-dimethyl-1,3-dioxan-2-yl]ethyl]-2-azetidinone is an intermediate in the synthesis of (3’R,3R,4R)-Ezetimibe (E974990), a structural analog of Ezetimibe (E975000). Ezetimibe is an antihyperlipoproteinemic and a cholesterol absorption inhibitor.
参考文献	van Heek, M., at al.: J. Pharmacol. Exp. Ther., 283, 157 (1997); van Heek, M., at al.: Brit. J. Pharmacol., 129, 1748 (2000)