产品编号：D473810

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	D473810
名称:	(4R)-3-[(2S)-2-[(S)-[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]phenyl][(4-fluorophenyl)amino]methyl]-4-[2-(4-fluorophenyl)-5,5-dimethyl-1,3-dioxan-2-yl]-1-oxobutyl]-4-phenyl-2-oxazolidinone
CAS号:	1478664-10-6
分子式:	C₄₄H₅₂F₂N₂O₆Si
外观:	白色固体
分子量:	770.98
溶解性:	DCM
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(4R)-3-[(2S)-2-[(S)-[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]phenyl][(4-fluorophenyl)amino]methyl]-4-[2-(4-fluorophenyl)-5,5-dimethyl-1,3-dioxan-2-yl]-1-oxobutyl]-4-phenyl-2-oxazolidinone is an intermediate in the synthesis of (3S,4S,3’S)-Ezetimbe (E975040), which is a 3-epimer impurity of Ezetimibe (E975000), a cholesterol absorption inhibitor.
参考文献	van Heek, M., at al.: J. Pharmacol. Exp. Ther., 283, 157 (1997), van Heek, M., at al.: Brit. J. Pharmacol., 129, 1748 (2000)