产品编号：D471915

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	D471915
名称:	3-(3,4-Dimethoxyphenyl)-1-methylpiperidine-2,4-dione
分子式:	C₁₄H₁₇NO₄
外观:	淡黄色固体
分子量:	263.29
溶解性:	Dichloromethane, Ethyl Acetate, Methanol
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	3-(3,4-Dimethoxyphenyl)-1-methylpiperidine-2,4-dione is an intermediate in the synthesis of Tolafentrine (T531000), which is a dual-selective phosphodiesterase 3/4 inhibitor used in chronic experimental pulmonary hypertension.
参考文献	Huxtable, R., et al.: Pharmacol. Ther., 47, 371 (1990), Tanaka, K., et al.: Cancer Res., 55, 2927 (1995), Wagner, R., et al.: J. Pharmacol. Exp. Ther., 282, 1650 (1997), Cowan, K., et al.: Nat. Med., 6, 698 (2000), Shankavaram, U., et al.: J. Biol. Chem., 276, 19027 (2001),