产品编号：D471595

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	D471595
名称:	3,5-Dimethyl 2-[(2-Azidoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-Pyridinedicarboxylic Acid Ester
CAS号:	1369501-85-8
分子式:	C₁₉H₂₁ClN₄O₅
分子量:	420.85
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	3,5-Dimethyl 2-[(2-Azidoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-Pyridinedicarboxylic Acid Ester is an intermediate used in the synthesis of Amlodipine Dimethyl Ester (A633560), which is Amlodipine Besilate (A633500) impurity, a dihydropyridine calcium channel blocker. Used as an antianginal and antihypertensive.
参考文献	Coburn, R., et al.: J. Med. Chem., 31, 2103 (1988), Gupta, S., et al.: Eur. J. Med. Chem., 38, 867 (2003), Vazzana, I., et al.: J. Med. Chem., 50, 334 (2007); Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986); Burges, R.A., et al.: J. Cardiovasc Pharmacol., 9, 110 (1987); Packer, M., et al.: N. Engl. J. Med., 335, 1107 (1996);