产品编号：D462095

产品规格：250mg

产品价格：面议

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产品详情

标准品编号:	D462095
名称:	N,N'-Dimethyl-N,N'-bis(2-pyridylmethyl)ethane-1,2-diamine
别名:	N,N'-Dimethyl-N,N'-bis(2-pyridylmethyl)ethylenediamine; N,N'-Dimethyl-N,N'-bis(pyridin-2-ylmethyl)-1,2-diaminoethane; N1,N2-Dimethyl-N1,N2-bis(2-pyridinylmethyl)-1,2-ethanediamine; N,N'-Bis(2-pyridylmethyl)-N,N'-dimethyl-1,2-ethanediamine
CAS号:	136768-57-5
分子式:	C₁₆H₂₂N₄
分子量:	270.37
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	N,N'-Dimethyl-N,N'-bis(2-pyridylmethyl)ethane-1,2-diamine is an intermediate used in the synthesis of 8-Hydroxy Efavirenz (H941830), which is a metabolite of Efavirenz (E425000), a non-nucleoside HIV-1 reverse transcriptase inhibitor. Also, it is a potential candidates for bioreductively activated prodrug.
参考文献	Gorski, J., et al.: Biochem. Pharmacol., 47, 1643 (1994), Desta, Z., et al.: J. Pharmacol. Exp. Ther., 285, 428 (1998), Langmann, P., et al.: Eur. J. Med. Res., 7, 309(2002), Chang, T., et al.: Drug Metab. Dispos., 31, 7 (2003); da Silva, A. F., et al.: Polyhedron, 123, 132-137 (2017)