产品编号：D460425

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	D460425
名称:	(R)-1-(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)-N,N-dimethylmethanamine
参考CAS号:	765853-00-7: non-chiral
分子式:	C₁₃H₁₉NO₂
分子量:	221.3
溶解性:	Chloroform, Dichloromethane, Ethyl Acetate, Methanol
种类:	Standards; Chiral Molecules;
应用:	(R)-1-(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)-N,N-dimethylmethanamine is an intermediate in the synthesis of ent-Ivabradine Hydrochloride (I940505), which is the enantiomer of Ivabradine Hydrochloride (I940500); a selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Also an antianginal.
参考文献	Thollon,C., et al.: Br. J. Pharmacol., 112, 37 (1994); Ragueneau, I., et al.: Clin. Pharmacol. Ther., 64, 192 (1998); Borer, J.S., et al.: Circulation, 107, 817 (2003); DiFrancesco, D., et al.: Drugs, 64, 1757 (2004)