产品编号：D455600
产品规格：10mg
产品价格：面议
| 标准品编号: | D455600 |
| 名称: | Di-O-cysteinyl-glycinoyl Curcumin 90% |
| 别名: | 4-((1E,6E)-7-(4-(2-((R)-2-Amino-3-mercaptopropanamido)acetoxy)-3-methoxyphenyl)-3,5-dioxohepta-1,6-dien-1-yl)-2-methoxyphenyl 2-((S)-2-amino-3-mercaptopropanamido)acetate; 2,2'-[[(1E,6E)-3,5-Dioxo-1,6-heptadiene-1,7-diyl]bis(2-methoxy-4,1-phenylene)] Ester L-Cysteinyl-glycine; |
| CAS号: | 1042019-87-3 |
| 分子式: | C₃₁H₃₆N₄O₁₀S₂ |
| 分子量: | 688.77 |
| 储存: | -20°C Freezer, Under inert atmosphere |
| 种类: | Standards; Amino Acids; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | Di-O-cysteinyl-glycinoyl curcumin is a metabolite of curcumin (C838500), which is a natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and antioxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope. Curcumin is currently being examined as a possible therapeutic for the treatment of Alzheimers disease ( |
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