产品编号：D454985

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	D454985
名称:	(2R,3R,11bS)-Dihydrotetrabenazine D-Val
分子式:	C₂₄H₃₈N₂O₄
分子量:	418.57
种类:	Research Tools; Standards; Molecular Biology; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(2R,3R,11bS)-Dihydrotetrabenazine D-Valis a related compound of (2S,3S,11bS)-Dihydrotetrabenazine (D454905).Tetrabenazineand dihydrotetrabenazines are potent inhibitors ofvesicular monoamine transporter 2(VMAT2). Furthermore, the derivatives of these compounds are potential drug candidates for treating various diseases such asHuntington’s disease and other hyperkinetic disorders.
参考文献	Yao, Z., et al.:ÂEur. J. Med. Chem. 46, 1841 (2011); Duffield, A. J. and Williams, N. A.ÂPCT Int. Appl. WOÂ2010026434ÂA1Â20100311 (2010); Grayson, B. et al.:ÂPCT Int. Appl. WOÂ2009150474ÂA1Â20091217 (2009); Nichols, P. P.ÂBrit. UK Pat. Appl. GBÂ2463451ÂAÂ20100317 (2010)