产品编号：D454345

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	D454345
名称:	11-​[2,​3-​Dihydro-​2-​[[2-​(3-​pyridinyl)​-​4-​quinazolinyl]​amino]​-​1H-​inden-​5-​yl]​-​, 2,​5-​dioxo-​1-​pyrrolidinyl ester 10-​Undecynoic acid
别名:	2,5-Dioxopyrrolidin-1-yl 11-(2-((2-(pyridin-3-yl)quinazolin-4-yl) amino)-2,3-dihydro-1H-inden-5-yl)undec-10-ynoate; JZ 5029;
CAS号:	2230167-11-8
分子式:	C₃₇H₃₇N₅O₄
分子量:	615.72
种类:	Research Tools; Molecular Biology; Enzyme Activators and Inhibitors;
应用:	11-​[2,​3-​Dihydro-​2-​[[2-​(3-​pyridinyl)​-​4-​quinazolinyl]​amino]​-​1H-​inden-​5-​yl]​-​, 2,​5-​dioxo-​1-​pyrrolidinyl ester 10-​Undecynoic acid is a lysine targeted inactivator used in the study for β-​Glucocerebrosidase (GCase) modulators and its dimerization resulting in allosteric binding site which could help with Parkinson's disease.
参考文献	Zheng, J., et al.: J. Am. Chem. Soc., 140, 5914-24 (2018);