产品编号：D451538

产品规格：250mg

产品价格：面议

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产品详情

标准品编号:	D451538
名称:	1,1-Difluoro-4-(iodomethyl)cyclohexane
CAS号:	476415-02-8
分子式:	C₇H₁₁F₂I
分子量:	260.06
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites; Anti-virals/Anti-retrovirals;
应用:	1,1-Difluoro-4-(iodomethyl)cyclohexane is derived from 4,4-Difluorocyclohexanecarboxylic Acid Ethyl Ester (D445698), which is used as a reactant in the preparation of antiretroviral drug Maraviroc (M193000), which is CCR-5 receptor antagonist used for treatment of HIV.
参考文献	Fumero, E., et al.: Clin. Microbiol. Infect., 9, 1077 (2003); Walker, D.K., et al.: Drug Metab. Dispos., 33, 587 (2005); Wood, A., et al.: Prog. Med. Chem., 43, 239 (2005); Haycock-Lewandowski, S., et al.: Org. Process Res. Dev., 12, 1094 (2008);