产品编号：D451653

产品规格：2.5g

产品价格：面议

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产品详情

标准品编号:	D451653
名称:	1-O-(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)-β-D-glucopyranuronic Acid 2,3,4-Triacetate Methyl Ester
别名:	(2S,3R,4S,5S,6S)-2-((1,3-Dioxoisoindolin-2-yl)oxy)-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl Triacetate;
CAS号:	319926-19-7
分子式:	C₂₁H₂₁NO₁₂
外观:	白色固体
分子量:	479.39
溶解性:	DCM, Ethyl Acetate
种类:	Standards; Carbohydrates and Oligosaccharides;
应用:	1-O-(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)-β-D-glucopyranuronic Acid 2,3,4-Triacetate Methyl Ester is an intermediate in synthesizing N-Hydroxy Vortioxetine O-β-D-Glucuronide Sodium Salt (H996005), which is a metabolite of Vortioxetine (V766000, HBr); a multimodal serotonergic agent which inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT.
参考文献	Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011); Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012); Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013); Uldam, H.K., et al.: Drug Metab. Dispos., 39, 2264 (2011);