产品编号：D450635

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	D450635
名称:	(2R,5S)-5-(3,4-Dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic Acid (1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl Ester
CAS号:	389128-28-3
分子式:	C₁₈H₂₆N₂O₅S
外观:	白色固体
分子量:	382.47
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(2R,5S)-5-(3,4-Dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic Acid (1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl Ester is an intermediate in the synthesis of (2R-cis)-1-[2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione which is an impurity of Lamivudine (L172500). (2R-cis)-1-[2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione is also being further studied to determine its potential as an anti-HIV agent.
参考文献	Jeong, L., et al.: J. Med. Chem., 36, 181 (1993)