产品编号：D448746

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	D448746
名称:	20β-Dihydrocortisol 21-Acetate
别名:	11β,17,20β,21-Tetrahydroxypregn-4-en-3-one 21-Acetate; (11β,20R)-21-(Acetyloxy)-11,17,20-trihydroxy-pregn-4-en-3-one;
CAS号:	66774-49-0
分子式:	C₂₃H₃₄O₆
分子量:	406.51
种类:	Standards; Miscellaneous; Steroids;
应用:	20β-Dihydrocortisol 21-Acetate is an intermediate in the synthesis of 20β-Dihydrocortisol (D448740), which could be used as a potential non invasive diagnostic test of transmissible spongiform encephalopaties. 20β-Dihydrocortisol is a metabolite of Cortisol (H714615), a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.
参考文献	Schelcher, F., et. al.: Endocrinology, 140, 2422 (1999); Phillipov, G., et. al.: J. Clin. Endocr. Metab., 81, 3855 (1996); Vigore, L., et al.: Cancer Ther., 6, 699 (2008); Puurunen, J., et al.: J. Clin. Endocrinol. Metab., 94, 1973 (2009); Lemos, D., et al.: J. Endocrinol., 201, 275 (2009); Chen, S., et al.: Am. J. Physiol., 296 (2009)