产品编号：D448720

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	D448720
名称:	6,7-Dihydrocanrenone
别名:	17-Hydroxy-3-oxo-17α-pregn-4-ene-21-carboxylic Acid γ-Lactone; 17β-Hydroxy-3-oxopregn-4-en-21-carboxylic Acid γ-Lactone; 3-(3-Oxo-17β-hydroxy-4-androsten-17-yl)propionic Acid γ-Lactone; 3-(3-Oxo-17β-hydroxyandrost-4-en-17α-yl)propiolactone; 3'-(3-Oxo-17β-hydroxyandrost-4-en-17α-yl)-propionic Acid Lactone; SC 5233; Spironolactone EP Impurity C;
杂质:	Spironolactone EP Impurity C
CAS号:	976-70-5
分子式:	C₂₂H₃₀O₃
外观:	白色至淡黄色固体
熔点:	>65°C (dec.)
分子量:	342.47
储存:	Hygroscopic, 冰箱保存, under inert atmosphere
溶解性:	Chloroform (Slightly), Methanol (Slightly)
种类:	Standards; Chiral Molecules; Steroids; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	6,7-Dihydrocanrenone (Spironolactone EP Impurity C) is an intermediate in the synthesis of Canrenone (C175610), an aldosterone antagonist. Diuretic.
参考文献	Sadee, W., et al.: J. Pharmacol. Exp. Ther., 185, 686 (1973); Pitt, B., et al.: Circulation, 108, 1831 (2003); Silvestre, J., et al.: J. Biol. Chem., 273, 4883 (1998); Struthers, A., et al.: Heart, 92, 1728 (2006)