产品编号：D447050

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	D447050
名称:	(2S,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane
别名:	1-[[(2S,3R)-2-(2,4-Difluorophenyl)-3-methyloxiranyl]methyl]-1H-1,2,4-triazole; (2S-cis)-1-[[2-(2,4-Difluorophenyl)-3-methyloxiranyl]methyl]-1H-1,2,4-triazole
CAS号:	135270-07-4
分子式:	C₁₂H₁₁F₂N₃O
分子量:	251.23
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(2S,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane is a useful synthetic intermediate in the synthesis of ent-Efinaconazole (E435075); the S,S-enantiomer of Efinaconazole (E435070) which is a topical antifungal for onychomycosis.
参考文献	Tasaka, A., et al.: Chem. Pharm. Bull., 41, 1035 (1993); Konosu, T., et al.: Chem. Pharm. Bull., 40, 562 (1992); Sugiura, K., et. al.: Antimicrob. Agents CH., 58, 3837 (2014)