产品编号：D446073

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	D446073
名称:	4,​4-​Difluoro-​N-​[(1S)​-​3-​hydroxy-​1-​phenylpropyl]​-cyclohexanecarboxami​de
别名:	4,4-Difluoro-N-((1S)-3-hydroxy-1-phenylpropyl)cyclohexanecarboxamide; UK 453465
CAS号:	376348-77-5
分子式:	C₁₆H₂₁F₂NO₂
外观:	白色固体
分子量:	297.34
溶解性:	Dichloromethane
种类:	Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	4,​4-​Difluoro-​N-​[(1S)​-​3-​hydroxy-​1-​phenylpropyl]​-cyclohexanecarboxami​de is an intermediate in synthesizing Maraviroc-d6 (M193002), a potent, non-competitive CCR5 receptor antagonist; inhibits binding of HIV viral coat protein gp120. Antiviral.
参考文献	Fumero, E., et al.: Clin. Microbiol. Infect., 9, 1077 (2003); Walker, D.K., et al.: Drug Metab. Dispos., 33, 587 (2005); Wood, A., et al.: Prog. Med. Chem., 43, 239 (2005)