产品编号：D445248

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	D445248
名称:	(S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl Isobutyl Carbonate
分子式:	C₂₇H₂₈N₂O₇
分子量:	492.52
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl Isobutyl Carbonate is an intermediate in the synthesis of 12-Hydroxy Irinotecan (Mixture of Diastereomers) (H943545). 12-Hydroxy Irinotecan is a metabolite of Irinotecan (I767500) found in human bile and urine.
参考文献	Lokeic, F. et al.: Clin. Cancer Res., 2, 1943 (1996); Dodds, H.M. et al.: Anti-cancer Drug Des., 16, 239 (2001); Kunimoto, T., et al.: Cancer Res., 47, 5944 (1987); Shimada, Y., et al.: J. Clin. Oncol., 11, 909 (1993)