产品编号：D439970

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	D439970
名称:	1,9-Dideoxyforskolin
别名:	[3R-(3α,4aβ,5β,6β,6aα,10aβ,10bα)]-5-(acetyloxy)-3-ethenyldodecahydro-6-hydroxy-3,4a,7,7,10a-pentamethyl-1H-Naphtho[2,1-b]pyran-1-one; -)-1,9-Dideoxyforskolin;1,9-Dideoxyforskolin;
CAS号:	64657-18-7
分子式:	C₂₂H₃₄O₅
分子量:	378.5
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	1,9-Dideoxyforkskolin does not activate adenylyl cyclase and is an inactive analog of Forskolin (F701800), a diterpene isolated from Coleus forskohlii, possessing vasodilating and cardiostimulatory properties. Forskolin resensitizes cell receptors by activating the enzyme adenylyl cyclase and increasing the intracellular levels of cAMP.
参考文献	Lindner, E., et al.: Arzneim.-Forsch., 28, 284 (1984), Hoever, G., et al.: J. Med. Chem., 48, 1256 (2005), Lai, S., et al.: Eur. J. Clin. Microbiol. Infect. Dis., 24, 5831 (2005); McHugh, E. et al.: J. Biol. Chem., 261, 3103 (1986);