产品编号：D438705

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	D438705
名称:	trans-N-[4-[2-[4-(2,3-Dichlorophenyl)piperazin-1-yl]ethyl]cyclohexyl]carbamic Acid Isopropyl Ester
别名:	Cariprazine Impurity 3, i-Pr Carbamate
CAS号:	1231947-90-2
分子式:	C₂₂H₃₃Cl₂N₃O₂
分子量:	442.42
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	trans-N-[4-[2-[4-(2,3-Dichlorophenyl)piperazin-1-yl]ethyl]cyclohexyl]carbamic Acid Isopropyl Ester, is an impurity of Cariprazine (C183490), an orally active D2/D3 dopamine receptor antagonist (1,2,3). Cariprazine is an antipsychotic drug candidate for the potential treatment of schizophrenia, bipolar mania and depression.
参考文献	Gruender, G.: Curr. Opin. Invest. Drugs, 11, 823 (2010); Seneca, N. et al.: Psychopharmacology, 218, 579 (2011); Kiss, B. et al.: J. Pharmacol. Exp. Therap., 333, 328 (2010);